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ZSTK474, a novel phosphatidylinositol 3-kinase inhibitor identified using the JFCR39 drug discovery system

JFCR39 is an informatic anticancer drug discovery system that utilizes a panel of 39 human cancer cells coupled with a drug-activity database. This system not only provides disease-oriented information but can also predict the mechanism of action of a given antitumor agent. Development of a phosphat...

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Detalhes bibliográficos
Main Authors: Kong, De-xin, Yamori, Takao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002321/
https://ncbi.nlm.nih.gov/pubmed/20729870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.150
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