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Enantio and Diastereoselective Addition of Phenylacetylene to Racemic α-chloroketones

In this report, we have presented the first diastereoselective addition of phenylacetylene to chiral racemic chloroketones. The addition is controlled by the reactivity of the chloroketones that allowed the stereoselective reaction to be performed at –20 °C. Chiral racemic chloroketones are used in...

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Bibliographic Details
Published in:Molecules
Main Authors: Alesi, Silvia, Emer, Enrico, Capdevila, Montse Guiteras, Petruzziello, Diego, Gualandi, Andrea, Cozzi, Pier Giorgio
Format: Artigo
Language:Inglês
Published: MDPI 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264675/
https://ncbi.nlm.nih.gov/pubmed/21701439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16065298
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