The Growth Suppressing Effects of Girinimbine on Hepg2 Involve Induction of Apoptosis and Cell Cycle Arrest

Murraya koenigii is an edible herb widely used in folk medicine. Here we report that girinimbine, a carbazole alkaloid isolated from this plant, inhibited the growth and induced apoptosis in human hepatocellular carcinoma, HepG2 cells. The MTT and LDH assay results showed that girinimbine decreased...

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Bibliographic Details
Published in:Molecules
Main Authors: Syam, Suvitha, Abdul, Ahmad Bustamam, Sukari, Mohd. Aspollah, Mohan, Syam, Abdelwahab, Siddig Ibrahim, Wah, Tang Sook
Format: Artigo
Language:Inglês
Published: MDPI 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264672/
https://ncbi.nlm.nih.gov/pubmed/21862957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16087155
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