The Growth Suppressing Effects of Girinimbine on Hepg2 Involve Induction of Apoptosis and Cell Cycle Arrest

Murraya koenigii is an edible herb widely used in folk medicine. Here we report that girinimbine, a carbazole alkaloid isolated from this plant, inhibited the growth and induced apoptosis in human hepatocellular carcinoma, HepG2 cells. The MTT and LDH assay results showed that girinimbine decreased...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Syam, Suvitha, Abdul, Ahmad Bustamam, Sukari, Mohd. Aspollah, Mohan, Syam, Abdelwahab, Siddig Ibrahim, Wah, Tang Sook
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264672/
https://ncbi.nlm.nih.gov/pubmed/21862957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16087155
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