Induction of selective cytotoxicity and apoptosis in human T4-lymphoblastoid cell line (CEMss) by boesenbergin a isolated from boesenbergia rotunda rhizomes involves mitochondrial pathway, activation of caspase 3 and G2/M phase cell cycle arrest

BACKGROUND: Boesenbergia rotunda (Roxb.) Schlecht (family zingiberaceae) is a rhizomatous herb that is distributed from north-eastern India to south-east Asia, especially in Indonesia, Thailand and Malaysia. Previous research has shown that the crude extract of this plant has cytotoxic properties. T...

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Autors principals: Ng, Kuan-Beng, Bustamam, Ahmad, Sukari, Mohd Aspollah, Abdelwahab, Siddig Ibrahim, Mohan, Syam, Buckle, Michael James Christopher, Kamalidehghan, Behnam, Nadzri, Nabilah Muhammad, Anasamy, Theebaa, A Hadi, A Hamid, Rahman, Heshu Sulaiman
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600682/
https://ncbi.nlm.nih.gov/pubmed/23432947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-13-41
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