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TargetClone: A multi-sample approach for reconstructing subclonal evolution of tumors

Most tumors are composed of a heterogeneous population of subclones. A more detailed insight into the subclonal evolution of these tumors can be helpful to study progression and treatment response. Problematically, tumor samples are typically very heterogeneous, making deconvolving individual tumor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Nieboer, Marleen M., Dorssers, Lambert C. J., Straver, Roy, Looijenga, Leendert H. J., de Ridder, Jeroen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264523/
https://ncbi.nlm.nih.gov/pubmed/30496231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208002
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