SubcloneSeeker: a computational framework for reconstructing tumor clone structure for cancer variant interpretation and prioritization

Many tumors are composed of genetically divergent cell subpopulations. We report SubcloneSeeker, a package capable of exhaustive identification of subclone structures and evolutionary histories with bulk somatic variant allele frequency measurements from tumor biopsies. We present a statistical fram...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Qiao, Yi, Quinlan, Aaron R, Jazaeri, Amir A, Verhaak, Roeland GW, Wheeler, David A, Marth, Gabor T
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Method
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180956/
https://ncbi.nlm.nih.gov/pubmed/25160522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0443-x
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller