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AAV8-mediated overexpression of mPCSK9 in liver differs between male and female mice
BACKGROUND AND AIMS: The recombinant adeno-associated viral vector serotype 8 expressing the gain-of-function mutation of mouse proprotein convertase subtilisin/kexin type 9 (AAV8- PCSK9) is a new model for the induction of hypercholesterolemia. AAV8 preferentially infects hepatocytes and the incorp...
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| Publicado no: | Atherosclerosis |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6263847/ https://ncbi.nlm.nih.gov/pubmed/30253291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2018.09.005 |
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