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Accelerated atherosclerosis development in C57Bl6 mice by overexpressing AAV-mediated PCSK9 and partial carotid ligation
Studying the role of a particular gene in atherosclerosis typically requires a time-consuming and often difficult process of generating double-knockouts or transgenics on ApoE(−/−) or LDL receptor(−/−) background. Recently, it was reported that adeno-associated-virus-8 (AAV8) mediated overexpression...
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| Gepubliceerd in: | Lab Invest |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5563968/ https://ncbi.nlm.nih.gov/pubmed/28504688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2017.47 |
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