A Model of Disturbed Flow-Induced Atherosclerosis in Mouse Carotid Artery by Partial Ligation and a Simple Method of RNA Isolation from Carotid Endothelium

Despite the well-known close association, direct evidence linking disturbed flow to atherogenesis has been lacking. We have recently used a modified version of carotid partial ligation methods [1,2] to show that it acutely induces low and oscillatory flow conditions, two key characteristics of distu...

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Главные авторы: Nam, Douglas, Ni, Chih-Wen, Rezvan, Amir, Suo, Jin, Budzyn, Klaudia, Llanos, Alexander, Harrison, David G., Giddens, Don P., Jo, Hanjoong
Формат: Artigo
Язык:Inglês
Опубликовано: MyJove Corporation 2010
Предметы:
JoVE Medicine
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153900/
https://ncbi.nlm.nih.gov/pubmed/20613706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/1861
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