Macrophage-associated lipin-1 enzymatic activity contributes to modified LDL-induced pro-inflammatory signaling and atherosclerosis

OBJECTIVE: Macrophage pro-inflammatory responses induced by modified low-density lipoproteins (modLDL) contribute to atherosclerotic progression. How modLDL causes macrophages to become pro-inflammatory is still enigmatic. Macrophage foam cell formation induced by modLDL requires glycerolipid synthe...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Vozenilek, Aimee E., Navratil, Aaron R., Green, Jonette M., Coleman, David T., Blackburn, Cassidy M.R., Finney, Alexandra C., Pearson, Brenna H., Chrast, Roman, Finck, Brian N., Klein, Ronald L., Orr, A. Wayne, Woolard, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785462/
https://ncbi.nlm.nih.gov/pubmed/29217509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310455
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