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In vitro assays for targeting and insertion of tail-anchored proteins into the ER membrane

Membrane proteins mediate numerous essential cellular functions. Due to the aggregation propensity of hydrophobic transmembrane domains in aqueous environments, the targeting and insertion of membrane proteins pose major challenges to cells. In the Guided Entry of Tail-anchored protein (GET) pathway...

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Détails bibliographiques
Publié dans:Curr Protoc Cell Biol
Auteurs principaux: Cho, Hyunju, Chio, Un Seng, Shan, Shu-ou
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263799/
https://ncbi.nlm.nih.gov/pubmed/30253068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpcb.63
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