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In vivo induction of membrane damage by β-amyloid peptide oligomers

Exposure to the β-amyloid peptide (Aβ) is toxic to neurons and other cell types, but the mechanism(s) involved are still unresolved. Synthetic Aβ oligomers can induce ion-permeable pores in synthetic membranes, but whether this ability to damage membranes plays a role in the ability of Aβ oligomers...

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Podrobná bibliografie
Vydáno v:Acta Neuropathol Commun
Hlavní autoři: Julien, Carl, Tomberlin, Colson, Roberts, Christine M., Akram, Aumbreen, Stein, Gretchen H., Silverman, Michael A., Link, Christopher D.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263551/
https://ncbi.nlm.nih.gov/pubmed/30497524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-018-0634-x
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