In vivo induction of membrane damage by β-amyloid peptide oligomers

Exposure to the β-amyloid peptide (Aβ) is toxic to neurons and other cell types, but the mechanism(s) involved are still unresolved. Synthetic Aβ oligomers can induce ion-permeable pores in synthetic membranes, but whether this ability to damage membranes plays a role in the ability of Aβ oligomers...

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Bibliographic Details
Published in:Acta Neuropathol Commun
Main Authors: Julien, Carl, Tomberlin, Colson, Roberts, Christine M., Akram, Aumbreen, Stein, Gretchen H., Silverman, Michael A., Link, Christopher D.
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263551/
https://ncbi.nlm.nih.gov/pubmed/30497524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-018-0634-x
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