The mechanistic insight of a specific interaction between 15d-Prostaglandin-J2 and eIF4A suggests an evolutionary conserved role across species

15-deoxy-delta 12,14-prostaglandin J2 (15d-PGJ2) is an anti-inflammatory/anti-neoplastic prostaglandin that functions through covalent binding to cysteine residues of various target proteins. We previously showed that 15d-PGJ2 mediated anti-inflammatory responses are dependent on the translational i...

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Udgivet i:Biol Open
Main Authors: Yun, So Jeong, Kim, Hyunjoon, Jung, Seung-Hyun, Kim, Joon Hyun, Ryu, Jeong Eun, Singh, N. Jiten, Jeon, Jouhyun, Han, Jin-Kwan, Kim, Cheol-Hee, Kim, Sanguk, Jang, Sung Key, Kim, Woo Jae
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262856/
https://ncbi.nlm.nih.gov/pubmed/30257829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.035402
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