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eIF2A mediates translation of hepatitis C viral mRNA under stress conditions
Translation of most mRNAs is suppressed under stress conditions. Phosphorylation of the α-subunit of eukaryotic translation initiation factor 2 (eIF2), which delivers initiator tRNA (Met-tRNA(i)) to the P site of the 40S ribosomal subunit, is responsible for such translational suppression. However,...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3116280/ https://ncbi.nlm.nih.gov/pubmed/21556050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.146 |
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