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Vangl2-dependent regulation of membrane protrusions and directed migration requires a fibronectin extracellular matrix

During zebrafish gastrulation the planar cell polarity (PCP) protein Vang-like 2 (Vangl2) regulates the polarization of cells that are engaged in directed migration. However, it is unclear whether Vangl2 influences membrane-protrusive activities in migrating gastrula cells and whether these processe...

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Bibliographic Details
Published in:Development
Main Authors: Love, Anna M., Prince, Dianna J., Jessen, Jason R.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262793/
https://ncbi.nlm.nih.gov/pubmed/30327324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.165472
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