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VANGL2 interacts with integrin αv to regulate matrix metalloproteinase activity and cell adhesion to the extracellular matrix

Planar cell polarity (PCP) proteins are implicated in a variety of morphogenetic processes including embryonic cell migration and potentially cancer progression. During zebrafish gastrulation, the transmembrane protein Vang-like 2 (VANGL2) is required for PCP and directed cell migration. These cell...

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Bibliographic Details
Published in:Exp Cell Res
Main Authors: Jessen, Tammy N., Jessen, Jason R.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701855/
https://ncbi.nlm.nih.gov/pubmed/29097183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2017.10.026
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