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Local extracellular matrix alignment directs cellular protrusion dynamics and migration through Rac1 and FAK

Cell migration within 3D interstitial microenvironments is sensitive to extracellular matrix (ECM) properties, but the mechanisms that regulate migration guidance by 3D matrix features remain unclear. To examine the mechanisms underlying the cell migration response to aligned ECM, which is prevalent...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Integr Biol (Camb)
Hauptverfasser: Carey, Shawn P., Goldblatt, Zachary E., Martin, Karen E., Romero, Bethsabe, Williams, Rebecca M., Reinhart-King, Cynthia A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980151/
https://ncbi.nlm.nih.gov/pubmed/27384462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ib00030d
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