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Vinculin regulates directionality and cell polarity in two- and three-dimensional matrix and three-dimensional microtrack migration
During metastasis, cells can use proteolytic activity to form tube-like “microtracks” within the extracellular matrix (ECM). Using these microtracks, cells can migrate unimpeded through the stroma. To investigate the molecular mechanisms of microtrack migration, we developed an in vitro three-dimens...
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| Publicado no: | Mol Biol Cell |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4850031/ https://ncbi.nlm.nih.gov/pubmed/26960796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-06-0432 |
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