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GCN5L1 interacts with αTAT1 and RanBP2 to regulate hepatic α-tubulin acetylation and lysosome trafficking

Although GCN5L1 (also known as BLOC1S1) facilitates mitochondrial protein acetylation and controls endosomal-lysosomal trafficking, the mechanisms underpinning these disparate effects are unclear. As microtubule acetylation modulates endosome-lysosome trafficking, we reasoned that exploring the role...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Wu, Kaiyuan, Wang, Lingdi, Chen, Yong, Pirooznia, Mehdi, Singh, Komudi, Wälde, Sarah, Kehlenbach, Ralph H., Scott, Iain, Gucek, Marjan, Sack, Michael N.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262773/
https://ncbi.nlm.nih.gov/pubmed/30333138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.221036
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