RanBP9 at the intersection between cofilin and Aβ pathologies: rescue of neurodegenerative changes by RanBP9 reduction

Molecular pathways underlying the neurotoxicity and production of amyloid β protein (Aβ) represent potentially promising therapeutic targets for Alzheimer's disease (AD). We recently found that overexpression of the scaffolding protein RanBP9 increases Aβ production in cell lines and in transge...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Woo, J A, Boggess, T, Uhlar, C, Wang, X, Khan, H, Cappos, G, Joly-Amado, A, De Narvaez, E, Majid, S, Minamide, L S, Bamburg, J R, Morgan, D, Weeber, E, Kang, D E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385917/
https://ncbi.nlm.nih.gov/pubmed/25741591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.37
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