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Development of an FVIII Inhibitor in a Mild Hemophilia Patient with a Phe595Cys Mutation

Mild hemophilia A is caused by a missense mutation in the FVIII gene that is responsible for a decrease in the FVIII:C to between 5% and 40%. The development of FVIII inhibitors has been reported in 3-13% of patients with mild hemophilia. Genetic risk factors for the development of inhibitors in mil...

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Detalhes bibliográficos
Publicado no:Intern Med
Main Authors: Yamanouchi, Jun, Tokumoto, Daiki, Ikeda, Yuichi, Maruta, Masaki, Kaneko, Masahiko, Hato, Takaaki, Yasukawa, Masaki
Formato: Artigo
Idioma:Inglês
Publicado em: The Japanese Society of Internal Medicine 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262709/
https://ncbi.nlm.nih.gov/pubmed/29877292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2169/internalmedicine.1145-18
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