Usefulness of Low-Dose Splenic Irradiation prior to Reduced-Intensity Conditioning Regimen for Hematopoietic Stem Cell Transplantation in Elderly Patients with Myelofibrosis

The Janus kinase (JAK) 1 and 2 inhibitor, ruxolitinib, was recently approved in Japan and has been effective in many patients with myelofibrosis (MF). Although the inhibitor decreases splenomegaly and relieves MF-related symptoms, allogeneic hematopoietic cell transplantation (HCT) remains as the on...

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Bibliographic Details
Published in:Case Rep Hematol
Main Authors: Matsubara, Etsuko, Yamanouchi, Jun, Kitazawa, Riko, Azuma, Taichi, Fujiwara, Hiroshi, Hato, Takaaki, Yasukawa, Masaki
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2016
Subjects:
Case Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093251/
https://ncbi.nlm.nih.gov/pubmed/27840748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8751329
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