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An Experimental Pipeline for Initial Characterization of Bacterial Type III Secretion System Inhibitor Mode of Action Using Enteropathogenic Yersinia

Dozens of Gram negative pathogens use one or more type III secretion systems (T3SS) to disarm host defenses or occupy a beneficial niche during infection of a host organism. While the T3SS represents an attractive drug target and dozens of compounds with T3SS inhibitory activity have been identified...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Cell Infect Microbiol
Egile Nagusiak: Morgan, Jessica M., Lam, Hanh N., Delgado, Jocelyn, Luu, Justin, Mohammadi, Sina, Isberg, Ralph R., Wang, Helen, Auerbuch, Victoria
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262202/
https://ncbi.nlm.nih.gov/pubmed/30524970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2018.00404
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