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Stabilization of the p53-DNA complex by the nuclear protein Dmp1α

We recently reported the existence of a physical interaction between the Myb-like transcription factor Dmp1 (Dmtf1) and p53 in which Dmp1 antagonized polyubiquitination of p53 by Mdm2 and promoted its nuclear localization. Dmp1 significantly stabilized p53-DNA complexes on promoters that contained p...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Invest
Egile Nagusiak: Kendig, Robert D., Kai, Fumitake, Fry, Elizabeth A., Inoue, Kazushi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262109/
https://ncbi.nlm.nih.gov/pubmed/28406729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07357907.2017.1303505
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