RollFISH achieves robust quantification of single-molecule RNA biomarkers in paraffin-embedded tumor tissue samples

Single-molecule RNA fluorescence in situ hybridization (smFISH) represents a promising approach to quantify the expression of clinically useful biomarkers in tumor samples. However, routine application of smFISH to formalin-fixed, paraffin-embedded (FFPE) samples is challenging due to the low signal...

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Vydáno v:Commun Biol
Hlavní autoři: Wu, Chenglin, Simonetti, Michele, Rossell, Carla, Mignardi, Marco, Mirzazadeh, Reza, Annaratone, Laura, Marchiò, Caterina, Sapino, Anna, Bienko, Magda, Crosetto, Nicola, Nilsson, Mats
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262000/
https://ncbi.nlm.nih.gov/pubmed/30511022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0218-0
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