Cold Formalin Fixation Guarantees DNA Integrity in Formalin Fixed Paraffin Embedded Tissues: Premises for a Better Quality of Diagnostic and Experimental Pathology With a Specific Impact on Breast Cancer

Formalin fixation and paraffin embedding (FFPE) represent the standard method to preserve tissue specimens for diagnostic pathology, however formalin fixation induces severe fragmentation of nucleic acids. We investigated whether formalin fixation at 4°C could preserve DNA integrity in FFPE specimen...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Front Oncol
Autori principali: Berrino, Enrico, Annaratone, Laura, Miglio, Umberto, Maldi, Elena, Piccinelli, Chiara, Peano, Erica, Balmativola, Davide, Cassoni, Paola, Pisacane, Alberto, Sarotto, Ivana, Venesio, Tiziana, Sapino, Anna, Marchiò, Caterina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042205/
https://ncbi.nlm.nih.gov/pubmed/32140450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00173
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi