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Cold Formalin Fixation Guarantees DNA Integrity in Formalin Fixed Paraffin Embedded Tissues: Premises for a Better Quality of Diagnostic and Experimental Pathology With a Specific Impact on Breast Cancer

Formalin fixation and paraffin embedding (FFPE) represent the standard method to preserve tissue specimens for diagnostic pathology, however formalin fixation induces severe fragmentation of nucleic acids. We investigated whether formalin fixation at 4°C could preserve DNA integrity in FFPE specimen...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Front Oncol
मुख्य लेखकों: Berrino, Enrico, Annaratone, Laura, Miglio, Umberto, Maldi, Elena, Piccinelli, Chiara, Peano, Erica, Balmativola, Davide, Cassoni, Paola, Pisacane, Alberto, Sarotto, Ivana, Venesio, Tiziana, Sapino, Anna, Marchiò, Caterina
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042205/
https://ncbi.nlm.nih.gov/pubmed/32140450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00173
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