Quantification of HER2 and estrogen receptor heterogeneity in breast cancer by single-molecule RNA fluorescence in situ hybridization

Intra-tumor heterogeneity is a pervasive property of human cancers that poses a major clinical challenge. Here, we describe the characterization, at the transcriptional level, of the intra-tumor topography of two prominent breast cancer biomarkers and drug targets, epidermal growth factor receptor 2...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Annaratone, Laura, Simonetti, Michele, Wernersson, Erik, Marchiò, Caterina, Garnerone, Silvano, Scalzo, Maria Stella, Bienko, Magda, Chiarle, Roberto, Sapino, Anna, Crosetto, Nicola
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper: Pathology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386639/
https://ncbi.nlm.nih.gov/pubmed/28423635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15727
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