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Prevention of neuronal apoptosis by astrocytes through thiol-mediated stress response modulation and accelerated recovery from proteotoxic stress

The development of drugs directly interfering with neurodegeneration has proven to be astonishingly difficult. Alternative therapeutic approaches could result from a better understanding of the supportive function of glial cells for stressed neurons. Therefore, here, we investigated the mechanisms i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Differ
Hauptverfasser: Gutbier, Simon, Spreng, Anna-Sophie, Delp, Johannes, Schildknecht, Stefan, Karreman, Christiaan, Suciu, Ilinca, Brunner, Thomas, Groettrup, Marcus, Leist, Marcel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261954/
https://ncbi.nlm.nih.gov/pubmed/30390092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0229-x
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