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Magnetic beads-based neuraminidase enzyme microreactor as a drug discovery tool for screening inhibitors from compound libraries and fishing ligands from natural products

Neuraminidase (NA) is a glycoside hydrolase that has been proposed as a potential therapeutic target for influenza. Thus, the identification of compounds that modulate NA activity could be of great therapeutic importance. The aim of this study is to develop a drug discovery tool for the identificati...

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Detalhes bibliográficos
Publicado no:J Chromatogr A
Main Authors: Zhao, Yu-Mei, Wang, Lv-Huan, Luo, Si-Fan, Wang, Qi-Qin, Moaddel, Ruin, Zhang, Ting-Ting, Jiang, Zheng-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261295/
https://ncbi.nlm.nih.gov/pubmed/30005943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2018.07.031
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