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HIV-1 immunogens and strategies to drive antibody responses towards neutralization breadth

Despite enormous efforts no HIV-1 vaccine has been developed that elicits broadly neutralizing antibodies (bNAbs) to protect against infection to date. The high antigenic diversity and dense N-linked glycan armor, which covers nearly the entire HIV-1 envelope protein (Env), are major roadblocks for...

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Bibliografiske detaljer
Udgivet i:Retrovirology
Main Authors: van Schooten, Jelle, van Gils, Marit J.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260891/
https://ncbi.nlm.nih.gov/pubmed/30477581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-018-0457-7
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