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Enhancer RNA and NFκB-dependent P300 regulation of ADAMDEC1

We observed increased expression of ADAMDEC1 RNA in monocytes from patients with systemic lupus erythematosus. The precise role of ADAMDEC1 is uncertain and uniquely among metalloproteinases it utilizes a zinc-coordinating aspartic acid residue which allows it to escape inhibition by tissue inhibito...

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Foilsithe in:Mol Immunol
Main Authors: Shi, Lihua, Song, Li, Maurer, Kelly, Zhang, Zhe, Petri, Michelle, Sullivan, Kathleen
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260809/
https://ncbi.nlm.nih.gov/pubmed/30352365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2018.09.019
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