Monocyte enhancers are highly altered in systemic lupus erythematosus

OBJECTIVE: Histone modifications set transcriptional competency and can perpetuate pathologic expression patterns. We defined systemic lupus erythematosus (SLE)-specific changes in H3K4me3 and K3K27me3, histone marks of gene activation and repression, respectively. METHODS: We used ChIP-seq to defin...

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Detalhes bibliográficos
Publicado no:Epigenomics
Main Authors: Shi, Lihua, Zhang, Zhe, Song, Li, Leung, Yiu Tak, Petri, Michelle A, Sullivan, Kathleen E
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864065/
https://ncbi.nlm.nih.gov/pubmed/26442457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi.15.47
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