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SERPINB2 is regulated by dynamic interactions with pause-release proteins and enhancer RNAs

The SERPINB2 gene is strongly upregulated in inflammatory states. In monocytes, it can constitute up to 1% of total cellular protein. It functions in protection from proteotoxic stress and plays a role in angioedema. The purpose of this study was to define the roles of enhancer RNAs embedded in the...

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Библиографические подробности
Опубликовано в: :Mol Immunol
Главные авторы: Shi, Lihua, Song, Li, Maurer, Kelly, Zhang, Zhe, Sullivan, Kathleen E.
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535806/
https://ncbi.nlm.nih.gov/pubmed/28578223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2017.05.005
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