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Glycopeptide Mimetics Recapitulate High-Mannose-Type Oligosaccharide Binding and Function
High-mannose-type glycans (HMTGs) decorating viral spike proteins are targets for virus neutralization. For carbohydrate-binding proteins, multivalency is important for high avidity binding and potent inhibition. To define the chemical determinants controlling multivalent interactions we designed gl...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6260803/ https://ncbi.nlm.nih.gov/pubmed/25776945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201500157 |
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