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Cardiovascular Small Heat Shock Protein HSPB7 Is a Kinetically Privileged Reactive Electrophilic Species (RES) Sensor

Small heat shock protein (sHSP)-B7 (HSPB7) is a muscle-specific member of the non-ATP-dependent sHSPs. The precise role of HSPB7 is enigmatic. Here, we disclose that zebrafish Hspb7 is a kinetically privileged sensor that is able to react rapidly with native reactive electrophilic species (RES), whe...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Surya, Sanjna L., Long, Marcus J. C., Urul, Daniel A., Zhao, Yi, Mercer, Emily J., EIsaid, Islam M., Evans, Todd, Aye, Yimon
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260788/
https://ncbi.nlm.nih.gov/pubmed/29397684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00925
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