Increased Autophagy Levels Mediate Cisplatin Resistance in Cisplatin-Resistant Cells While Also Rendering Them Vulnerable to Autophagy Induction

Autophagy plays an important role in tumor development because of its capacity to maintain energy homeostasis by recycling damaged intracellular proteins and organelles, and increased autophagy levels are reported to mediate drug resistance in many cancers. However, whether high autophagy levels neg...

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Vydáno v:Biomed Res Int
Hlavní autoři: Duan, Guihua, Song, Zhengji, Qi, Min, Bai, Xuan, Wang, Jingzhai, Zhang, Yu, Zou, Xiaoping, Guo, Qiang, Wan, Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260253/
https://ncbi.nlm.nih.gov/pubmed/30539004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/1736738
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