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A Strategy to Delay the Development of Cisplatin Resistance by Maintaining a Certain Amount of Cisplatin-Sensitive Cells

Cisplatin (ddp), which is commonly employed in the treatment of many advanced cancers, often results in initial therapeutic success; however, rapid progression of ddp-resistant cells remains the main reason for treatment failure. Facd with such a problem, we investigated the fitness differences betw...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Duan, Guihua, Tang, Qianyuan, Yan, Hongli, Xie, Lijuan, Wang, Yun, Zheng, Xi Emily, Zhuge, Yuzheng, Shen, Shanshan, Zhang, Bin, Zhang, Xiaoqi, Wang, Jun, Wang, Wei, Zou, Xiaoping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428423/
https://ncbi.nlm.nih.gov/pubmed/28348367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00422-2
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