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Increased Autophagy Levels Mediate Cisplatin Resistance in Cisplatin-Resistant Cells While Also Rendering Them Vulnerable to Autophagy Induction

Autophagy plays an important role in tumor development because of its capacity to maintain energy homeostasis by recycling damaged intracellular proteins and organelles, and increased autophagy levels are reported to mediate drug resistance in many cancers. However, whether high autophagy levels neg...

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Bibliografske podrobnosti
izdano v:Biomed Res Int
Main Authors: Duan, Guihua, Song, Zhengji, Qi, Min, Bai, Xuan, Wang, Jingzhai, Zhang, Yu, Zou, Xiaoping, Guo, Qiang, Wan, Ping
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260253/
https://ncbi.nlm.nih.gov/pubmed/30539004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/1736738
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