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Efficacy Versus Hepatotoxicity of High-dose Rifampin, Pyrazinamide, and Moxifloxacin to Shorten Tuberculosis Therapy Duration: There Is Still Fight in the Old Warriors Yet!
BACKGROUND: One approach that could increase the efficacy and reduce the duration of antituberculosis therapy is pharmacokinetics/pharmacodynamics-based optimization of doses. However, this could increase toxicity. METHODS: We mimicked the concentration-time profiles achieved by human equivalent dos...
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| Publicado no: | Clin Infect Dis |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6260156/ https://ncbi.nlm.nih.gov/pubmed/30496465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciy627 |
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