Targeting phosphorylated p53 to elicit tumor-reactive T helper responses against head and neck squamous cell carcinoma

The human T cell receptor is capable of distinguishing between normal and post-translationally modified peptides. Because aberrant phosphorylation of cellular proteins is a hallmark of malignant transformation, the expression of the phosphorylated epitope could be an ideal antigen to combat cancer w...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncoimmunology
Prif Awduron: Ohara, Kenzo, Ohkuri, Takayuki, Kumai, Takumi, Nagato, Toshihiro, Nozaki, Yui, Ishibashi, Kei, Kosaka, Akemi, Nagata, Marino, Harabuchi, Shohei, Ohara, Mizuho, Oikawa, Kensuke, Aoki, Naoko, Harabuchi, Yasuaki, Celis, Esteban, Kobayashi, Hiroya
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2018
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6259824/
https://ncbi.nlm.nih.gov/pubmed/30510853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1466771
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