A Simplified Liquid Chromatography-Mass Spectrometry Assay for Artesunate and Dihydroartemisinin, Its Metabolite, in Human Plasma

Artesunate (AS) is a potent antimalarial that is used worldwide for the treatment of malaria. A simple method with a total run time of 12 min was developed and validated for the quantification of AS and dihydroartemisinin (DHA), its active metabolite, in human (heparinized) plasma based on one-step...

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Detaylı Bibliyografya
Yayımlandı:Molecules
Asıl Yazarlar: Teja-Isavadharm, Paktiya, Siriyanonda, Duangsuda, Siripokasupkul, Raveewan, Apinan, Roongnapa, Chanarat, Nitima, Lim, Apassorn, Wannaying, Srisombat, Saunders, David, Fukuda, Mark M., Miller, Robert S., Weina, Peter J., Meléndez, Victor
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6259473/
https://ncbi.nlm.nih.gov/pubmed/21124272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules15128747
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