Pharmacokinetics and Pharmacodynamics of Oral Artesunate Monotherapy in Patients with Uncomplicated Plasmodium falciparum Malaria in Western Cambodia

Artemisinin-resistant malaria along the Thailand-Cambodian border is an important public health concern, yet mechanisms of drug action and their contributions to the development of resistance are poorly understood. The pharmacokinetics and pharmacodynamics of oral artesunate monotherapy were explore...

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Autors principals: Saunders, David, Khemawoot, Phisit, Vanachayangkul, Pattaraporn, Siripokasupkul, Raveewan, Bethell, Delia, Tyner, Stuart, Se, Youry, Rutvisuttinunt, Wiriya, Sriwichai, Sabaithip, Chanthap, Lon, Lin, Jessica, Timmermans, Ans, Socheat, Doung, Ringwald, Pascal, Noedl, Harald, Smith, Bryan, Fukuda, Mark, Teja-isavadharm, Paktiya
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486599/
https://ncbi.nlm.nih.gov/pubmed/22869581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00044-12
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