Pharmacokinetics and Pharmacodynamics of Oral Artesunate Monotherapy in Patients with Uncomplicated Plasmodium falciparum Malaria in Western Cambodia

Artemisinin-resistant malaria along the Thailand-Cambodian border is an important public health concern, yet mechanisms of drug action and their contributions to the development of resistance are poorly understood. The pharmacokinetics and pharmacodynamics of oral artesunate monotherapy were explore...

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Detalhes bibliográficos
Main Authors: Saunders, David, Khemawoot, Phisit, Vanachayangkul, Pattaraporn, Siripokasupkul, Raveewan, Bethell, Delia, Tyner, Stuart, Se, Youry, Rutvisuttinunt, Wiriya, Sriwichai, Sabaithip, Chanthap, Lon, Lin, Jessica, Timmermans, Ans, Socheat, Doung, Ringwald, Pascal, Noedl, Harald, Smith, Bryan, Fukuda, Mark, Teja-isavadharm, Paktiya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486599/
https://ncbi.nlm.nih.gov/pubmed/22869581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00044-12
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