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SMuRF: a novel tool to identify regulatory elements enriched for somatic point mutations

BACKGROUND: Single Nucleotide Variants (SNVs), including somatic point mutations and Single Nucleotide Polymorphisms (SNPs), in noncoding cis-regulatory elements (CREs) can affect gene regulation and lead to disease development. Several approaches have been developed to identify highly mutated regio...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Guilhamon, Paul, Lupien, Mathieu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258448/
https://ncbi.nlm.nih.gov/pubmed/30477433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2501-y
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