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Targeting Junctional Adhesion Molecule-C Ameliorates Sepsis-induced Acute Lung Injury by Decreasing CXCR4(+) Aged Neutrophils
Sepsis is a severe inflammatory condition causing high mortality. Transmigration of neutrophils into tissues increases their lifespan to promote deleterious function. Junctional adhesion molecule-C (JAM-C) plays a pivotal role in neutrophil transmigration into tissues. We aim to study the role of JA...
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| Publié dans: | J Leukoc Biol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6258282/ https://ncbi.nlm.nih.gov/pubmed/30088666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3A0218-050R |
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