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Extracellular CIRP generates a pro-inflammatory Ly6G(+)CD11b(hi) subset of low-density neutrophils in sepsis

Extracellular cold-inducible RNA-binding protein (eCIRP) is a damage-associated molecular pattern. Neutrophils present in the mononuclear cell fraction of Ficoll gradient separation are called low-density neutrophils (LDNs). Here we report the novel role of eCIRP on LDN’s heterogeneity in sepsis. Se...

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Podrobná bibliografie
Vydáno v:J Leukoc Biol
Hlavní autoři: Takizawa, Satoshi, Murao, Atsushi, Ochani, Mahendar, Aziz, Monowar, Wang, Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8053202/
https://ncbi.nlm.nih.gov/pubmed/33070370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3HI0620-416R
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