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Global and Pathway-specific Transcriptional Regulations of Pactamycin Biosynthesis in Streptomyces pactum

Pactamycin, a structurally unique aminocyclitol natural product isolated from Streptomyces pactum, has potent antibacterial, anti-tumor and anti-protozoa activities. However, its production yields under currently used culture conditions are generally low. To understand how pactamycin biosynthesis is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Appl Microbiol Biotechnol
Hauptverfasser: Lu, Wanli, Alanzi, Abdullah R., Abugrain, Mostafa E., Ito, Takuya, Mahmud, Taifo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258269/
https://ncbi.nlm.nih.gov/pubmed/30276712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-018-9375-9
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