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Real time genetic compensation defines the dynamic demands of feedback control

Biological signaling networks use feedback control to dynamically adjust their operation in real time. Traditional static genetic methods such as gene knockouts or rescue experiments often can identify the existence of feedback interactions, yet are unable to determine what feedback dynamics are req...

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Dettagli Bibliografici
Pubblicato in:Cell
Autori principali: Harrigan, Patrick, Madhani, Hiten D., El-Samad, Hana
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258208/
https://ncbi.nlm.nih.gov/pubmed/30340045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.09.044
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