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Real time genetic compensation defines the dynamic demands of feedback control

Biological signaling networks use feedback control to dynamically adjust their operation in real time. Traditional static genetic methods such as gene knockouts or rescue experiments often can identify the existence of feedback interactions, yet are unable to determine what feedback dynamics are req...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Harrigan, Patrick, Madhani, Hiten D., El-Samad, Hana
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258208/
https://ncbi.nlm.nih.gov/pubmed/30340045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.09.044
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